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首页-抗体药物偶连体和PROTACs-PROTAC-dTAGV-1 hydrochloride
dTAGV-1 hydrochloride

Chemical Structure : dTAGV-1 hydrochloride

CAS No.: 2624313-16-0

dTAGV-1 hydrochloride (dTAG(V)-1)

货号: PC-23665Not For Human Use, Lab Use Only.

dTAGV-1 hydrochloride is an exclusively selective VHL-recruiting dTAG molecule, to rapidly degrade FKBP12F36V-tagged proteins.

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2 mg ¥2980 In stock
5 mg ¥4980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

dTAGV-1 hydrochloride is an exclusively selective VHL-recruiting dTAG molecule, to rapidly degrade FKBP12F36V-tagged proteins.

物理化学性质&存储条件

分子量 1284.01
分子式 C68H91ClN6O14S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-3-(3,4-dimethoxyphenyl)-1-(2-(2-((7-(((S)-1-((2S,4R)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-7-oxoheptyl)amino)-2-oxoethoxy)phenyl)propyl (S)-1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)piperidine-2-carboxylate hydrochloride

参考文献

1. Dezhi Li, et al. J Clin Invest. 2024 Dec 24:e174249.

2. Nabet B, et al. Nat Commun. 2020 Sep 18;11(1):4687.

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