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首页-小分子抑制剂&激动剂-GPCR-Amylin receptor (AMYR)-Zenagamtide sodium
Zenagamtide sodium

Chemical Structure : Zenagamtide sodium

CAS No.:

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Zenagamtide sodium (Amycretin, NN 9487)

货号: PC-27448Not For Human Use, Lab Use Only.

Zenagamtide sodium (Amycretin, NN 9487) is a unimolecular peptide, orally active, blood-brain barrier permeable triple agonist of GLP-1, amylin, and calcitonin receptors, significantly suppresses appetite and reduces energy intake, improves body weight, waist circumference, glycated hemoglobin and lipid profile, and also alleviates the histological features of metabolic dysfunction-associated steatotic liver disease (MASLD) and enhances insulin sensitivity.

规格 价格 库存 数量
2 mg ￥2480 In stock
5 mg ￥3980 In stock
10 mg ￥5880 In stock
50 mg Get quote
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Zenagamtide sodium (Amycretin, NN 9487) is a unimolecular peptide, orally active, blood-brain barrier permeable triple agonist of GLP-1, amylin, and calcitonin receptors, significantly suppresses appetite and reduces energy intake, improves body weight, waist circumference, glycated hemoglobin and lipid profile, and also alleviates the histological features of metabolic dysfunction-associated steatotic liver disease (MASLD) and enhances insulin sensitivity.

物理化学性质&存储条件

分子量 7846.60 (free base)
分子式 C343H550N94O116.xNa
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Glu-Gln-Ala-Ala-Arg-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-{Lys(AEEA-AEEA-γGlu-C18 diacid)}-Gly-Gly-Gly-Gly-Glu-Ala-Ser-Glu-Leu-Ser-Thr-Ala-Ala-Leu-Gly-Arg-Leu-Ser-Ala-Glu-Leu-His-Glu-Leu-Ala-Thr-Leu-Pro-Arg-Thr-Glu-Thr-Gly-Ser-Gly-Ser-Pro-NH2

参考文献

1. Mora P, et al. Lancet. 2026 Jul 30:S0140-6736(26)01247-X.

2. Oldenburg LIK, et al. Diabetes Obes Metab. 2026 Jul 13.

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