Zardaverine

Chemical Structure : Zardaverine

CAS No.: 101975-10-4

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货号: PC-25667Not For Human Use, Lab Use Only.

规格	价格	库存
10 mg	￥780	In stock
25 mg	￥1280	In stock
50 mg	￥1980	In stock
100 mg		Get quote

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生物&药学活性

Zardaverinea is a potent, specific PDE III/IV (PDE3/4) inhibitor, inhibits PDE III from human platelets and the rolipram-inhibitable PDE IV from canine trachea and human polymorphonuclear (PMN) cells with IC50 of 0.58, 0.79 and 0.17uM, respectively.
Zardaverine inhibits the ADP-induced aggregation of human platelets with an IC50 of 1.6 uM.
Zardaverine inhibits the zymosan-induced superoxide anion generation with IC50 of 0.4 uM in human PMN cells.

物理化学性质&存储条件

分子量	268.22
分子式	C12H10F2N2O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	6-(4-(Difluoromethoxy)-3-methoxyphenyl)pyridazin-3(2H)-one

参考文献

1. Schudt C, et al. Agents Actions Suppl. 1991;34:379-402.

2. Schudt C, et al. Biochem Pharmacol. 1991 Jun 21;42(1):153-62.

Zardaverine

生物&药学活性

物理化学性质&存储条件

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Zardaverine

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