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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-HCN Channel-ZD7288
ZD7288

Chemical Structure : ZD7288

CAS No.: 133059-99-1

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ZD7288 (ICI-D 7288, ZD-7288)

货号: PC-70127Not For Human Use, Lab Use Only.

ZD7288 (ICI-D 7288) is a selective hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker.

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10 mg ￥1480 In stock
25 mg ￥2580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

ZD7288 (ICI-D 7288) is a selective hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker.
ZD7288 inhibits the hyperpolarization activated cationic current (If) in a concentration-dependent manner in rat brain.

物理化学性质&存储条件

分子量 292.81
分子式 C15H21ClN4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(Z)-N-ethyl-1,2-dimethyl-6-(methylimino)-N-phenyl-1,6-dihydropyrimidin-4-amine hydrochloride

参考文献

1. Zhang XX, et al. Neural Regen Res. 2016 May;11(5):779-86.

2. Guli X, et al. Neural Plast. 2012;2012:237913.

3. BoSmith RE, et al. Br J Pharmacol. 1993 Sep;110(1):343-9.

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