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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Potassium Channel-Z299576254
Z299576254

Chemical Structure : Z299576254

CAS No.: 1210503-30-2

Z299576254

货号: PC-28404Not For Human Use, Lab Use Only.

Z299576254 is a safe and potent voltage-gated potassium channel Kv1.3 inhibitor, suppresses macrophage inflammatory responses by modulating the PI3K/AKT signaling pathway.

规格 价格 库存 数量
25 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Z299576254 is a safe and potent voltage-gated potassium channel Kv1.3 inhibitor, suppresses macrophage inflammatory responses by modulating the PI3K/AKT signaling pathway.
Z299576254 suppresses the inflammatory response in RAW264.7 cells
Z299576254 ameliorates alcoholic liver injury by inhibiting Kv1.3.
Z299576254 exerts anti-inflammatory effects via the PI3K/AKT signaling pathway.

物理化学性质&存储条件

分子量 495.60
分子式 C25H29N5O4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-((2-(cyclohexyl(methyl)amino)-2-oxoethyl)thio)-N-(2-oxo-2-((2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)amino)ethyl)benzamide

参考文献

1. Wen-Jun Zhen, et al. Eur J Med Chem. 2026 Sep 19:320:119310.

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