Z247611722 | Serine palmitoyltransferase inhibitor, Antifungal

Chemical Structure : Z247611722

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Z247611722 (Z-247611722)

货号: PC-28604Not For Human Use, Lab Use Only.

Z247611722 is a novel antifungal, inhibitor of sphingolipid biosynthesis and serine palmitoyltransferase (SPT), displays fungicidal activity against multiple Candida species (C. albicans, MIC=1.56 uM) and fluconazole-resistant isolates.

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生物&药学活性

Z247611722 is a novel antifungal, inhibitor of sphingolipid biosynthesis and serine palmitoyltransferase (SPT), displays fungicidal activity against multiple Candida species (C. albicans, MIC=1.56 uM) and fluconazole-resistant isolates.

物理化学性质&存储条件

分子量	345.29
分子式	C16H12FN3O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(1,3-dimethyl-2,4,7-trioxo-1,3,4,7-tetrahydro-2H-pyrano[2,3-d]pyrimidin-6-yl)-4-fluorobenzamide

参考文献

1. Nysten J, et al. Nat Commun. 2026 Sep 15;17(1):10813.

Z247611722 (Z-247611722)

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物理化学性质&存储条件

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Z247611722 (Z-247611722)

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物理化学性质&存储条件

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