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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Stearoyl-CoA Desaturase (SCD)-YTX-465
YTX-465

Chemical Structure : YTX-465

CAS No.: 2225824-53-1

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YTX-465 (YTX465, YTX 465)

货号: PC-35915Not For Human Use, Lab Use Only.

YTX-465 (YTX465) is a specific small molecule that rescues yeast from a-Syn cytotoxicity with EC50 of 15 nM, via inhibiting Ole1, the yeast homolog of human stearoyl-CoA desaturase (SCD).

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2 mg ￥1880 In stock
5 mg ￥2980 In stock
10 mg ￥4780 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

YTX-465 (YTX465) is a specific small molecule that rescues yeast from a-Syn cytotoxicity with EC50 of 15 nM, via inhibiting Ole1, the yeast homolog of human stearoyl-CoA desaturase (SCD).
YTX-465 is inactive at SCD1.

物理化学性质&存储条件

分子量 458.522
分子式 C25H26N6O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(2-(4-(3-(1,3-dimethyl-1H-indazol-6-yl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)-2-oxoethyl)benzamide

参考文献

1. Vincent BM, et al. Cell Rep. 2018 Dec 4;25(10):2742-2754.e31.

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