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首页-小分子抑制剂&激动剂-TGF-beta/Smad-TGF beta Receptor (TGFBR)-YR-290
YR-290

Chemical Structure : YR-290

CAS No.: 883560-84-7

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YR-290

货号: PC-24982Not For Human Use, Lab Use Only.

YR-290 is a specific inhibitor of TGFβ receptor 1 (TGFβR1) with IC50 of 137 nM, exhibits anticancer activity of IC50 value of 9.13 μM against A549 cell.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

YR-290 is a specific inhibitor of TGFβ receptor 1 (TGFβR1) with IC50 of 137 nM, exhibits anticancer activity of IC50 value of 9.13 μM against A549 cell.

物理化学性质&存储条件

分子量 290.37
分子式 C19H18N2O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-phenyl-1-(1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)ethan-1-one

参考文献

1. Fang Y, et al. J Natl Cancer Inst. 2013 Jan 2;105(1):47-58.

2. Zhang J, et al. Eur J Med Chem. 2025 May 5;289:117442.

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