YL-IPA08

Chemical Structure : YL-IPA08

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货号: PC-24504Not For Human Use, Lab Use Only.

YL-IPA08 is a potent and selective TSPO ligand with high affinity (IC50 = 0.23 nM).

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生物&药学活性

YL-IPA08 is a potent and selective TSPO ligand with high affinity (IC50 = 0.23 nM).
YL-IPA08 produced significant antidepressant-like and anxiolytic-like effects in a series of mouse and rat behavior models, antidepressant-like behavior of YL-IPA08 was totally blocked by the TSPO antagonist PK11195.
YL-IPA08 had no myorelaxant effects and did not affect the motor coordination, memory or hexobarbitone-induced sleep in mice.

物理化学性质&存储条件

分子量	475.80
分子式	C23H21Cl3N4O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(2-(3,4-dichlorophenyl)-7-methylimidazo[1,2-a]pyridin-3-yl)-N-ethyl-N-(pyridin-2-yl)acetamide hydrochloride

参考文献

1. Zhang LM, et al. Neuropharmacology. 2014 Jun;81:116-25.

YL-IPA08

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物理化学性质&存储条件

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YL-IPA08

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物理化学性质&存储条件

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