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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-PARP-YCH3292
YCH3292

Chemical Structure : YCH3292

CAS No.: 3049753-10-5

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YCH3292 (YCH-3292)

货号: PC-27880Not For Human Use, Lab Use Only.

YCH3292 is a potent, new-generation antiresistant PARP inhibitor with IC50 of <0.001 nM for PARP1/2, exhibits robust antiproliferative activity against Capan-1/TP cells with IC50 of 0.23 nM, overcomes acquired resistance to PARPi.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

YCH3292 is a potent, new-generation antiresistant PARP inhibitor with IC50 of <0.001 nM for PARP1/2, exhibits robust antiproliferative activity against Capan-1/TP cells with IC50 of 0.23 nM, overcomes acquired resistance to PARPi.

物理化学性质&存储条件

分子量 510.52
分子式 C28H23FN6O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1(2H)-Phthalazinone, 4-[[3-[[3-(5-cyclopropyl-2-furanyl)-5,6-dihydro-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]carbonyl]-4-fluorophenyl]methyl]-

参考文献

1. Sun Y, et al. Eur J Med Chem. 2026 Feb 15;304:118507.

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