WX-02-16

Chemical Structure : WX-02-16

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货号: PC-27911Not For Human Use, Lab Use Only.

WX-02-16 is an enantioselective covalent inhibitor of BAX, dose-dependently suppresses tBID-triggered, BAX-mediated mitochondrial cytochrome c release, shows covalent engagement of BAX Cys126, protects cells from BAX-dependent apoptosis in HCT116 cells and primary DRG neurons.

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25 mg		Get quote
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100 mg		Get quote

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生物&药学活性

WX-02-16 is an enantioselective covalent inhibitor of BAX, dose-dependently suppresses tBID-triggered, BAX-mediated mitochondrial cytochrome c release, shows covalent engagement of BAX Cys126, protects cells from BAX-dependent apoptosis in HCT116 cells and primary DRG neurons.

物理化学性质&存储条件

分子量	431.49
分子式	C25H25N3O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(1S,3S)-2-acryloyl-1-(benzo[d][1,3]dioxol-5-yl)-N-propyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxamide

参考文献

1. Shi P, et al. Nat Chem Biol. 2026 Aug 28. doi: 10.1038/s41589-026-02297-9.

WX-02-16

生物&药学活性

物理化学性质&存储条件

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WX-02-16

生物&药学活性

物理化学性质&存储条件

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