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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Parasite-WJM280
WJM280

Chemical Structure : WJM280

CAS No.:

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WJM280

货号: PC-24372Not For Human Use, Lab Use Only.

WJM280 is a potent, specific inhibitor of P. falciparum mitochondrial protein cytochrome b (Pf cyt b), inhibits LDH activity of P. falciparum 3D7 parasites with EC50 of 40 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

WJM280 is a potent, specific inhibitor of P. falciparum mitochondrial protein cytochrome b (Pf cyt b), inhibits LDH activity of P. falciparum 3D7 parasites with EC50 of 40 nM.

物理化学性质&存储条件

分子量 390.45
分子式 C22H25F3N2O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-Cyclopropyl-4-((propyl(4-(trifluoromethyl)benzyl)amino)methyl)benzamide

参考文献

1. Awalt JK, et al. Eur J Med Chem. 2024 Dec 15;280:116921.

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