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首页-小分子抑制剂&激动剂-Epigenetics-Histone Methyltransferase (HMTase)-WDR5-0103
WDR5-0103

Chemical Structure : WDR5-0103

CAS No.: 890190-22-4

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WDR5-0103 (WD-Repeat Protein 5-0103)

货号: PC-45617Not For Human Use, Lab Use Only.

A potent MLL1-WDR5 interaction inhibitor with IC50 of 26.4 nM in competitive binding assay.

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5 mg (Free Sample) ￥280 In stock
10 mg ￥780 In stock
25 mg ￥1380 In stock
50 mg ￥2180 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

WDR5-0103 is a potent MLL1-WDR5 interaction inhibitor with IC50 of 26.4 nM in competitive binding assay.
WDR5-0103 inhibits the catalytic activity of MLL1 complex with IC50 value of 5.4 uM.

物理化学性质&存储条件

分子量 383.4409
分子式 C21H25N3O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 40 mg/mL
Chemical Name/SMILES

Benzoic acid, 3-[(3-methoxybenzoyl)amino]-4-(4-methyl-1-piperazinyl)-, methyl ester

参考文献

1. Li DD, et al. Bioorg Med Chem. 2016 Nov 15;24(22):6109-6118.

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