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首页-小分子抑制剂&激动剂-Epigenetics-Histone Methyltransferase (HMTase)-WCJ-394
WCJ-394

Chemical Structure : WCJ-394

CAS No.:

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WCJ-394 (WCJ394)

货号: PC-28671Not For Human Use, Lab Use Only.

WCJ-394 is a potent PRMT1 inhibitor with IC50 of 1.21 uM, exhibits similar inhibitory activities against PRMT4 and PRMT8, weakly inhibits PRMT3 and PRMT6.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

WCJ-394 is a potent PRMT1 inhibitor with IC50 of 1.21 uM, exhibits similar inhibitory activities against PRMT4 and PRMT8, weakly inhibits PRMT3 and PRMT6.

物理化学性质&存储条件

分子量 326.85
分子式 C13H19ClN6S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5-(4-(((2-aminoethyl)(methyl)amino)methyl)thiazol-2-yl)picolinimidamide hydrochloride

参考文献

1. Caijiao Wang, et al. Front Chem. 2022 Jun 8:10:888727.

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