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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Glutamate Transporter-WAY-213613 hydrochloride
WAY-213613 hydrochloride

Chemical Structure : WAY-213613 hydrochloride

CAS No.: 2450268-84-3

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WAY-213613 hydrochloride (WAY213613 hydrochloride)

货号: PC-28282Not For Human Use, Lab Use Only.

WAY-213613 hydrochloride (WAY213613) is a potent, non-substrate inhibitor of EAAT2 (GLT-1) with IC50 of 85 nM, displays > 44-fold selectivity over EAAT1 and EAAT3.

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5 mg ￥980 In stock
10 mg ￥1480 In stock
25 mg ￥2580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

WAY-213613 hydrochloride (WAY213613) is a potent, non-substrate inhibitor of EAAT2 (GLT-1) with IC50 of 85 nM, displays > 44-fold selectivity over EAAT1 and EAAT3.
WAY-213613 also exhibits no activity towards ionotropic and metabotropic glutamate receptors.

物理化学性质&存储条件

分子量 451.65
分子式 C16H14BrClF2N2O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-[4-(2-Bromo-4,5-difluorophenoxy)phenyl]-L-asparagine hydrochloride

参考文献

1. Dunlop J, et al. Mol Pharmacol. 2005 Oct;68(4):974-82.

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