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首页-抗体和重组蛋白-Biosimilar Antibody-Vopratelimab
Vopratelimab

Chemical Structure : Vopratelimab

CAS No.: 2039148-04-2

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Vopratelimab (JTX-2011)

货号: PC-38868Not For Human Use, Lab Use Only.

Vopratelimab (JTX-2011) is an agonist monoclonal antibody that binds to and activates ICOS, the Inducible T cell CO-Stimulator, a protein on the surface of certain T cells commonly found in many solid tumors.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Vopratelimab (JTX-2011) is an agonist monoclonal antibody that binds to and activates ICOS, the Inducible T cell CO-Stimulator, a protein on the surface of certain T cells commonly found in many solid tumors.
Vopratelimab (JTX-2011) requires initial T cell priming and Fc cross-linking for optimal T cell activation and anti-tumor immunity.

Isotype: IgG1-kappa.

Anti-[human ICOS (Inducible T-cell COStimulator, CD278)], human monoclonal antibody.

物理化学性质&存储条件

分子量
分子式
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

参考文献

1. Amanda Hanson, et al. PLoS One. 2020 Sep 24;15(9):e0239595.

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