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首页-小分子抑制剂&激动剂-Cytoskeleton/Cell Adhesion Molecules-Microtubule/Tubulin-Verubulin
Verubulin

Chemical Structure : Verubulin

CAS No.: 827031-83-4

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Verubulin (MPC6827, MPC-6827)

货号: PC-25919Not For Human Use, Lab Use Only.

Verubulin (MPC-6827) is a microtubule-destabilizing agent and microtubule formation inhibitor, effectively inhibits the polymerization of tubulin in vitro, inhibits cancer cell lines regardless of the expression levels of the multidrug resistance ABC transporters MDR-1 (Pgp-1), MRP-1, and BCRP-1.

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10 mg ￥880 In stock
25 mg ￥1380 In stock
50 mg ￥2180 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Verubulin (MPC-6827) is a microtubule-destabilizing agent and microtubule formation inhibitor, effectively inhibits the polymerization of tubulin in vitro, inhibits cancer cell lines regardless of the expression levels of the multidrug resistance ABC transporters MDR-1 (Pgp-1), MRP-1, and BCRP-1.

物理化学性质&存储条件

分子量 279.34
分子式 C17H17N3O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(4-Methoxyphenyl)-N,2-dimethylquinazolin-4-amine

参考文献

1. Kasibhatla S, et al. Cancer Res. 2007 Jun 15;67(12):5865-71.

2. Sirisoma N, et al. J Med Chem. 2009 Apr 23;52(8):2341-51.

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