欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-抗体和重组蛋白-Biosimilar Antibody-Vedolizumab
Vedolizumab

Chemical Structure : Vedolizumab

CAS No.: 943609-66-3

加入收藏

Vedolizumab (Anti-human α4β7 mAb, human IgG1-Kappa; MLN-0002)

货号: PC-Ab1072Not For Human Use, Lab Use Only.

Vedolizumab (MLN-0002) is a humanized monoclonal antibody, which acts against α 4 β 7 integrin heterodimer and blocks the interaction of α4β7 integrin with mucosal address in cell adhesion molecule-1 (MAdCAM-1). Vedolizumab inhibits the migration of memory T-lymphocytes across the endothelium into inflamed gastrointestinal (GI) parenchymal tissue, impairs the migration of gut-homing lymphocytes into the mucosa, thereby acting as a gut-selective anti-lymphocyte-trafficking immunomodulator..

规格 价格 库存 数量
1 mg ￥3580 In stock
5 mg ￥7580 In stock
10 mg ￥12800 In stock
100 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Vedolizumab (MLN-0002) is a humanized monoclonal antibody, which acts against α 4 β 7 integrin heterodimer and blocks the interaction of α4β7 integrin with mucosal address in cell adhesion molecule-1 (MAdCAM-1). Vedolizumab inhibits the migration of memory T-lymphocytes across the endothelium into inflamed gastrointestinal (GI) parenchymal tissue, impairs the migration of gut-homing lymphocytes into the mucosa, thereby acting as a gut-selective anti-lymphocyte-trafficking immunomodulator.

物理化学性质&存储条件

分子量
分子式 Human IgG1-Kappa
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES

Vedolizumab; Entyvio; MLN-0002; LDP-02; LPD-02; MLN-002; 943609-66-3; Anti-Human lymphocyte α4β7 integrin; Alpha4beta7 integrin; anti-human Integrin; 943609-66-3

参考文献

1. 1, Soler D, et al. J Pharmacol Exp Ther. 2009 Sep;330(3):864-75. 2, Feagan BG, et al. Clin Gastroenterol Hepatol. 2008 Dec;6(12):1370-7. 3, Feagan BG, et al. N Engl J Med. 2013 Aug 22;369(8):699-710. 4, Sandborn WJ, et al. N Engl J Med. 2013 Aug 22;369(8):711-21.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: