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Vav1 inhibitor AB19

Chemical Structure : Vav1 inhibitor AB19

CAS No.:

Vav1 inhibitor AB19 (Vav1C1 inhibitor)

货号: PC-25627Not For Human Use, Lab Use Only.

Vav1 inhibitor AB19 is a small molecule inhibitor of guanine nucleotide exchange factor Vav1 atypical C1 domain (Vav1C1), effectly inhibits proliferation of Vav1-expressing cells, inhibits growth of patient-derived organoids models of pancreatic cancer.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Vav1 inhibitor AB19 is a small molecule inhibitor of guanine nucleotide exchange factor Vav1 atypical C1 domain (Vav1C1), effectly inhibits proliferation of Vav1-expressing cells, inhibits growth of patient-derived organoids models of pancreatic cancer.

物理化学性质&存储条件

分子量 538.61
分子式 C29H48BrNO3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(2-(2-(hydroxymethyl)-5-oxo-4-(propan-2-ylidene)tetrahydrofuran-2-yl)ethyl)-1-tetradecylpyridin-1-ium bromide salt

参考文献

1. Bellomo A, et al. ChemMedChem. 2025 Oct 20:e202500589.

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