Varlilumab |CAS:1393344-72-3 Probechem Biochemicals

Chemical Structure : Varlilumab

CAS No.: 1393344-72-3

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Varlilumab (Anti-human CD27 mAb, human IgG4P-Kappa; CDX-1127)

货号: PC-Ab1082Not For Human Use, Lab Use Only.

Varlilumab (CDX-1127) is a novel, first-in-class fully human IgG1 kappa anti-CD27 monoclonal antibody that acts as an agonist of CD27 by interaction with the CD70-binding site. Varlilumab (CDX-1127) stimulates the CD27 pathway, which results in T-cell activation and antitumor activity in tumor models..

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1 mg	￥3580	In stock
5 mg	￥7580	In stock
10 mg	￥12800	In stock
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生物&药学活性

物理化学性质&存储条件

分子量
分子式	Human IgG4P-Kappa
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES	Varlilumab; CDX-1127; CDX1127; Anti-human TNFRSF7; 1F5; 1393344-72-3; anti human CD27; Cluster of differentiation 27

参考文献

1. 1, Ansell SM, et al. Blood Adv. 2020 May 12;4(9):1917-1926. 2, Burris HA, et al. J Clin Oncol. 2017 Jun 20;35(18):2028-2036. 3, Ramakrishna V, et al. J Immunother Cancer. 2015 Aug 18;3:37. 4, Turaj AH, et al. Cancer Cell. 2017 Dec 11;32(6):777-791.e6.

Varlilumab (Anti-human CD27 mAb, human IgG4P-Kappa; CDX-1127)

生物&药学活性

物理化学性质&存储条件

参考文献

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Varlilumab (Anti-human CD27 mAb, human IgG4P-Kappa; CDX-1127)

生物&药学活性

物理化学性质&存储条件

参考文献

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