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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-CFTR-Vanzacaftor
Vanzacaftor

Chemical Structure : Vanzacaftor

CAS No.: 2374124-49-7

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Vanzacaftor (VX-121, VX121)

货号: PC-73453Not For Human Use, Lab Use Only.

Vanzacaftor (VX-121) is a potent, selective cystic fibrosis transmembrane regulator (CFTR) corrector, with potential for treatment of cystic fibrosis.

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5 mg ￥2180 In stock
10 mg ￥3480 In stock
25 mg ￥5480 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Vanzacaftor (VX-121) is a potent, selective cystic fibrosis transmembrane regulator (CFTR) corrector, with potential for treatment of cystic fibrosis.

物理化学性质&存储条件

分子量 617.76
分子式 C32H39N7O4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

13H-17,20-Methano-8,12-nitrilo-12H-pyrido[3,2-d][1,2,6,13]thiatriazacyclooctadecin-5(6H)-one, 2-[3-(2-dispiro[2.0.2.1]hept-7-ylethoxy)-1H-pyrazol-1-yl]-14,15,16,17,18,19-hexahydro-19,19-dimethyl-, 7,7-dioxide, (17S)-

参考文献

1. Aaron Kolski-Andreaco, et al. J Clin Invest. 2024 Jul 2:e176328.

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