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首页-小分子抑制剂&激动剂-Ras-Raf-MAPK-ERK Pathway-MEKK (MAP3K)-VU6083859
VU6083859

Chemical Structure : VU6083859

CAS No.: 3128174-48-8

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VU6083859 (VU 6083859, VU-6083859)

货号: PC-25989Not For Human Use, Lab Use Only.

VU6083859 is a potent, selective The thousand and one (TAO) kinase TAOK1 inhibitor with IC50 of 158 nM, shows 22- and >63-fold selectivity over TAOK2 and TAOK3.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    VU6083859 is a potent, selective The thousand and one (TAO) kinase TAOK1 inhibitor with IC50 of 158 nM, shows 22- and >63-fold selectivity over TAOK2 and TAOK3.

    物理化学性质&存储条件

    分子量 467.49
    分子式 C26H24F3N3O2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (S)-N-(3-oxo-3-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)propyl)-4-(2-(trifluoromethyl)pyridin-4-yl)benzamide

    参考文献

    1. Schultz DC, et al. ACS Chem Neurosci. 2026 Jan 13. doi: 10.1021/acschemneuro.5c00906.

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