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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Potassium Channel-VU6080824
VU6080824

Chemical Structure : VU6080824

CAS No.:

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VU6080824 (VU 6080824)

货号: PC-25574Not For Human Use, Lab Use Only.

VU6080824 is a potent, selective inhibitor of the inward-rectifier potassium channel Kir2.1 with IC50 of 5.9 uM in Kir2.1 thallium flux assays, selective relative to Kir1.1 and Kir4.1 up to 10 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

VU6080824 is a potent, selective inhibitor of the inward-rectifier potassium channel Kir2.1 with IC50 of 5.9 uM in Kir2.1 thallium flux assays, selective relative to Kir1.1 and Kir4.1 up to 10 uM.

物理化学性质&存储条件

分子量 333.43
分子式 C22H23NO2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-(3'-Methoxy-[1,1'-biphenyl]-4-yl)-N-(4-methoxybenzyl)methanamine

参考文献

1. Duncan RA, et al. ACS Med Chem Lett. 2025 Aug 29;16(9):1762-1771.

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