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首页-小分子抑制剂&激动剂-GPCR-mAChR-VU6052254
VU6052254

Chemical Structure : VU6052254

CAS No.: 3035701-02-8

VU6052254

货号: PC-26504Not For Human Use, Lab Use Only.

VU6052254 is a potent, selective muscarinic acetylcholine receptor subtype 1 (M1) positive allosteric modulator (PAM) with EC50 of 59 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

VU6052254 is a potent, selective muscarinic acetylcholine receptor subtype 1 (M1) positive allosteric modulator (PAM) with EC50 of 59 nM.

物理化学性质&存储条件

分子量 448.47
分子式 C25H22F2N4O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

6-(2,6-difluoro-4-(7-(2-hydroxypropan-2-yl)-2-methyl-2H-indazol-4-yl)benzyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one

参考文献

1. Julie L Engers, et al. ACS Chem Neurosci. 2025 Dec 17;16(24):4741-4750.

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