VU6016235

Chemical Structure : VU6016235

加入收藏

货号: PC-24342Not For Human Use, Lab Use Only.

VU6016235 is a potent, selective, orally active M4 mAChR positive allosteric modulator (PAM) with EC50 of 140 nM (hM4), has >148-fold selectivity over other subtypes mAChRs.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

VU6016235 is a potent, selective, orally active M4 mAChR positive allosteric modulator (PAM) with EC50 of 140 nM (hM4), has >148-fold selectivity over other subtypes mAChRs.
VU6016235 (1-10 mg/kg), administered orally, reverses amphetamine-induced hyperlocomotion in male Sprague–Dawley rats.

物理化学性质&存储条件

分子量	378.49
分子式	C21H22N4OS
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(4-(((2,4-dimethylpyrido[4',3':4,5]thieno[2,3-d]pyrimidin-8-yl)amino)methyl)phenyl)propan-2-ol

参考文献

1. Engers JL, et al. ACS Chem Neurosci. 2024 Sep 24;15(20):3744-54.

VU6016235

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

VU6016235

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.