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首页-小分子抑制剂&激动剂-GPCR-mGluR-VU6001192
VU6001192

Chemical Structure : VU6001192

CAS No.: 1821325-29-4

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VU6001192 (VU-6001192)

货号: PC-27119Not For Human Use, Lab Use Only.

VU6001192 is a potent and highly selective mGlu2 negative allosteric modulator (NAM) with IC50 of 207 nM in calcium mobilization mGlu2 assays, is inactive against mGlu3 up to 30 uM

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

VU6001192 is a potent and highly selective mGlu2 negative allosteric modulator (NAM) with IC50 of 207 nM in calcium mobilization mGlu2 assays, is inactive against mGlu3 up to 30 uM

物理化学性质&存储条件

分子量 409.46
分子式 C23H24FN3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

6-(((2S,6R)-2,6-dimethylmorpholino)methyl)-1-(4-fluorophenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide

参考文献

1. Felts AS, et al. J Med Chem. 2015 Nov 25;58(22):9027-40.

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