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首页-小分子抑制剂&激动剂-Cytoskeleton/Cell Adhesion Molecules-Kinesin-VLS-1488
VLS-1488

Chemical Structure : VLS-1488

CAS No.: 2914879-10-8

VLS-1488 (VLS1488, KIF18A-IN-6)

货号: PC-25961Not For Human Use, Lab Use Only.

VLS-1488 (KIF18A-IN-6) is a potent, selective and orally active KIF18A inhibitor, inhibits KIF18A microtubule-dependent ATPase activity with IC50 of 16 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

VLS-1488 (KIF18A-IN-6) is a potent, selective and orally active KIF18A inhibitor, inhibits KIF18A microtubule-dependent ATPase activity with IC50 of 16 nM.

物理化学性质&存储条件

分子量 559.74
分子式 C28H37N3O5S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(tert-butyl)-3-(5''-(ethylsulfonamido)dispiro[cyclopropane-1,1'-cyclohexane-4',3''-indoline]-1''-carbonyl)benzenesulfonamide

参考文献

1. Patent WO2023028564 (Compound 134).

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