VE-821 |CAS:1232410-49-9 Probechem Biochemicals

Chemical Structure : VE-821

CAS No.: 1232410-49-9

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VE-821 (VE821;VE 821)

货号: PC-44042Not For Human Use, Lab Use Only.

VE-821 (VE821) is a potent, selective and ATP-competitive inhibitor of ATR with Ki/IC50 of 13 nM/26 nM, respectively.

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5 mg	￥580	In stock
10 mg	￥880	In stock
25 mg	￥1280	In stock
50 mg	￥2180	In stock
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生物&药学活性

VE-821 (VE821) is a potent, selective and ATP-competitive inhibitor of ATR with Ki/IC50 of 13 nM/26 nM, respectively.
VE-821 shows excellent selectivity for ATR over the related PIKKs ATM, DNA-PK, mTOR and PI3K.

物理化学性质&存储条件

分子量	368.4096
分子式	C18H16N4O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Pyrazinecarboxamide, 3-amino-6-[4-(methylsulfonyl)phenyl]-N-phenyl-

参考文献

1. Reaper PM, et al. Nat Chem Biol, 2011, 7(7), 428-430.

2. Charrier JD, et al. J Med Chem, 2011, 54(7), 2320-2330.

3. Prevo R, et al. Cancer Biol Ther. 2012 Sep;13(11):1072-81.

VE-821 (VE821;VE 821)

生物&药学活性

物理化学性质&存储条件

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VE-821 (VE821;VE 821)

生物&药学活性

物理化学性质&存储条件

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