VASH1-VASH2 inibitor LV87

Chemical Structure : VASH1-VASH2 inibitor LV87

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货号: PC-25427Not For Human Use, Lab Use Only.

LV87 is a potent, selective and covalent inhibitor of tubulin detyrosinating enzymes VASH1 and VASH2 with IC50 of 0.01 and 0.06 uM respectively, inhibits tubulin detyrosination.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

LV87 is a potent, selective and covalent inhibitor of tubulin detyrosinating enzymes VASH1 and VASH2 with IC50 of 0.01 and 0.06 uM respectively, inhibits tubulin detyrosination.

物理化学性质&存储条件

分子量	646.70
分子式	C34H38N4O9
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-3-(4-(Benzyloxy)phenyl)-2-((2S,3S)-3-(((S)-6-(hydroxyamino)-1,6-dioxo-1-(phenethylamino)hexan-2-yl)carbamoyl)oxirane-2-carboxamido)propanoic Acid

参考文献

1. Feral A, et al. J Med Chem. 2025 Aug 25. doi: 10.1021/acs.jmedchem.5c00980.