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首页-小分子抑制剂&激动剂-GPCR-Calcium-sensing Receptor (CaSR)-Upacicalcet
Upacicalcet

Chemical Structure : Upacicalcet

CAS No.: 1333218-50-0

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Upacicalcet

货号: PC-61402Not For Human Use, Lab Use Only.

Upacicalcet is a novel positive allosteric modulator of the calcium-sensing receptor (CaSR), a novel secondary hyperparathyroidism drug that targets the amino acid binding site of CaSR.

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5 mg ￥2280 In stock
10 mg ￥3880 In stock
25 mg ￥5980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Upacicalcet is a novel positive allosteric modulator of the calcium-sensing receptor (CaSR), a novel secondary hyperparathyroidism drug that targets the amino acid binding site of CaSR.

物理化学性质&存储条件

分子量 351.758
分子式 C11H14ClN3O6S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(2S)-2-amino-3-{[(3-chloro-2-methyl-5-sulfophenyl)carbamoyl]amino}propanoic acid

参考文献

1, Sato H, et al. Mol Pharmacol. 2022 Oct;102(4):183-195.
2, Sato H, et al. Bone. 2023 Feb;167:116613.

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