USP7i-1 |CAS:1381291-36-6 Probechem Biochemicals

Chemical Structure : USP7i-1

CAS No.: 1381291-36-6

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货号: PC-61935Not For Human Use, Lab Use Only.

USP7i-1 (USP7-IN-1) is a potent, selective USP7 inhibitor with IC50 of 77 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

USP7i-1 (USP7-IN-1) is a potent, selective USP7 inhibitor with IC50 of 77 uM.

USP7i-1 shows no inhibition of USP8, USP5, Uch-L1, Uch-L3 or caspase 3.

USP7i-1 inhibits the proliferation of HCT116 cells with GI50 of 67 uM.

分子量	425.913
分子式	C23H24ClN3O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	7-chloro-3-((4-hydroxy-1-(3-phenylpropanoyl)piperidin-4-yl)methyl)quinazolin-4(3H)-one

1. Weisberg EL, et al. Nat Chem Biol. 2017 Dec;13(12):1207-1215.

2. Kessler BM. Expert Opin Ther Pat. 2014 May;24(5):597-602.

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