USP5 inhibitor 64 (USP5-IN-1)

Chemical Structure : USP5 inhibitor 64

CAS No.: 2851040-81-6

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货号: PC-72414Not For Human Use, Lab Use Only.

USP5 inhibitor 64 (USP5-IN-1) is a selective chemical probe (inhibitor) against USP5 deubiquitinase, binds to the USP5 ZnF-UBD (zinc-finger ubiquitin binding domain) with KD of 2.8 uM.

规格	价格	库存
5 mg	￥1580	In stock
10 mg	￥2380	In stock
25 mg	￥3880	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

USP5 inhibitor 64 (USP5-IN-1) is a selective chemical probe (inhibitor) against USP5 deubiquitinase, binds to the USP5 ZnF-UBD (zinc-finger ubiquitin binding domain) with KD of 2.8 uM.
USP5 inhibitor 64 is selective over nine proteins containing structurally similar ZnF-UBD domains.
USP5 inhibitor 64 inhibits the USP5 catalytic cleavage of a di-ubiquitin substrate in an in vitro assay.

物理化学性质&存储条件

分子量	437.895
分子式	C19H20ClN3O5S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility
Chemical Name/SMILES	(5-((4-(4-chlorophenyl)piperidin-1-yl)sulfonyl)picolinoyl)glycine

参考文献

1. Mandeep K Mann, et al. J Med Chem. 2021 Oct 28;64(20):15017-15036.