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首页-小分子抑制剂&激动剂-Proteasome/Ubiquitin-Deubiquitinase (DUB)-USP20 inhibitor C2
USP20 inhibitor C2

Chemical Structure : USP20 inhibitor C2

CAS No.: 923689-60-5

USP20 inhibitor C2

货号: PC-27899Not For Human Use, Lab Use Only.

USP20 inhibitor C2 is a small molecule Ubiquitin-Specific Protease 20 (USP20) inhibitor with IC50 of 13.55 uM (300 nM Ub-Rho110 as substrate), directly deubiquitinates and stabilizes fatty acid synthase (FASN), suppresses de novo lipogenesis (DNL) to alleviate MASLD.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

USP20 inhibitor C2 is a small molecule Ubiquitin-Specific Protease 20 (USP20) inhibitor with IC50 of 13.55 uM (300 nM Ub-Rho110 as substrate), directly deubiquitinates and stabilizes fatty acid synthase (FASN), suppresses de novo lipogenesis (DNL) to alleviate MASLD.

物理化学性质&存储条件

分子量 400.43
分子式 C24H20N2O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-[2-(4-ethoxyphenyl)-4-oxo-4H-chromen-6-yl]-1-phenylurea

参考文献

1. Ma X, et al. Pharmacol Res. 2026 Aug 19;232:108406.

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