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首页-小分子抑制剂&激动剂-Proteasome/Ubiquitin-Deubiquitinase (DUB)-USP11 inhibitor 26
USP11 inhibitor 26

Chemical Structure : USP11 inhibitor 26

CAS No.:

USP11 inhibitor 26 (USP11-IN-1)

货号: PC-26236Not For Human Use, Lab Use Only.

USP11 inhibitor 26 (USP11-IN-1) is a selective inhibitor of USP11 with IC50 of 10.9 uM, shows 1.7- and >100-fold selective over USP4 and USP15.

规格 价格 库存 数量
25 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

USP11 inhibitor 26 (USP11-IN-1) is a selective inhibitor of USP11 with IC50 of 10.9 uM, shows 1.7- and >100-fold selective over USP4 and USP15.
USP11 inhibitor 26 reduced the viability of platin-resistant ovarian cancer cells (PEO4) with IC50 of 0.47 uM.

物理化学性质&存储条件

分子量 452.95
分子式 C20H25ClN4O4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(4-chlorobenzyl)-1-methyl-4-(2-(4-(methylsulfonyl)piperazin-1-yl)acetyl)-1H-pyrrole-2-carboxamide

参考文献

1. Hassan MA, et al. ACS Omega. 2025 Dec 5;10(49):60555-60571.

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