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首页-小分子抑制剂&激动剂-Epigenetics-Histone Methyltransferase (HMTase)-UNC7648
UNC7648

Chemical Structure : UNC7648

CAS No.:

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UNC7648 (UNC 7648)

货号: PC-21490Not For Human Use, Lab Use Only.

UNC7648 is a small molecule inhibitor of the methyl-lysine reader p53 binding protein 1 (53BP1) tandem Tudor domain (TTD) with TR-FRET IC50 of 8.6 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    UNC7648 is a small molecule inhibitor of the methyl-lysine reader p53 binding protein 1 (53BP1) tandem Tudor domain (TTD) with TR-FRET IC50 of 8.6 uM.

    物理化学性质&存储条件

    分子量 611.79
    分子式 C35H45N7O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (S)-N-((2'-((1-amino-1-oxo-6-(pyrrolidin-1-yl)hexan-2-yl)carbamoyl)-[1,1'-biphenyl]-2-yl)methyl)-4-(4-methylpiperazin-1-yl)picolinamide

    参考文献

    1. Devan J Shell, et al. SLAS Discov. 2022 Dec;27(8):428-439.

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