UNC0631 | G9a inhibitor | Probechem Biochemicals

Chemical Structure : UNC0631

CAS No.: 1320288-19-4

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UNC0631 (UNC-0631, UNC 0631)

货号: PC-25272Not For Human Use, Lab Use Only.

UNC0631 (UNC 0631) is a potent, selective and cell-active inhibitor of G9a methyltransferase with IC50 of 4 nM in SAHH-coupled assays, reduces H3K9me2 levels in MDA-MB-231 cells with IC50 of 25 nM.

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5 mg	￥580	In stock
10 mg	￥880	In stock
25 mg	￥1380	In stock
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生物&药学活性

UNC0631 (UNC 0631) is a potent, selective and cell-active inhibitor of G9a methyltransferase with IC50 of 4 nM in SAHH-coupled assays, reduces H3K9me2 levels in MDA-MB-231 cells with IC50 of 25 nM.

物理化学性质&存储条件

分子量	635.94
分子式	C37H61N7O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(1-(Cyclohexylmethyl)piperidin-4-yl)-2-(4-isopropyl-1,4-diazepan-1-yl)-6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinazolin-4-amine

参考文献

1. Liu F, et al. J Med Chem. 2011 Sep 8;54(17):6139-50.

UNC0631 (UNC-0631, UNC 0631)

生物&药学活性

物理化学性质&存储条件

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UNC0631 (UNC-0631, UNC 0631)

生物&药学活性

物理化学性质&存储条件

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