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首页-小分子抑制剂&激动剂-Immunology/Inflammation-STING-UM-232
UM-232

Chemical Structure : UM-232

CAS No.:

UM-232 (UM232)

货号: PC-27260Not For Human Use, Lab Use Only.

UM-232 is a selecitve, next-generation, covalent STING inhibitor wth EC50 of 2.6 uM in THP1 R232 cells, inhibits STING oligomerization.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

UM-232 is a selecitve, next-generation, covalent STING inhibitor wth EC50 of 2.6 uM in THP1 R232 cells, inhibits STING oligomerization.

物理化学性质&存储条件

分子量 535.09
分子式 C29H35ClN6O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-((S)-4-(4-([1,1'-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl)-5-oxo-5-(2-oxa-7-azaspiro[3.5]nonan-7-yl)pentyl)-2-chloropropanimidamide

参考文献

1. Barasa L, et al. ACS Med Chem Lett. 2026 Jun 19;17(7):1547-1554.

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