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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Potassium Channel-UK-78282 hydrochloride
UK-78282 hydrochloride

Chemical Structure : UK-78282 hydrochloride

CAS No.: 136647-02-4

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UK-78282 hydrochloride (UK-78,282, UK78282 )

货号: PC-28189Not For Human Use, Lab Use Only.

UK-78282 hydrochloride is a selective inhibitor of Kv1.3 voltage-gated potassium channel with IC50 of 200 nM, shows preferentially blocking and binding to the C-type inactivated state of the channel, displays marked selectivity for Kv1.3 over other closely related K+ channels.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

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UK-78282 hydrochloride is a selective inhibitor of Kv1.3 voltage-gated potassium channel with IC50 of 200 nM, shows preferentially blocking and binding to the C-type inactivated state of the channel, displays marked selectivity for Kv1.3 over other closely related K+ channels.

物理化学性质&存储条件

分子量 466.06
分子式 C29H36ClNO2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-((Benzhydryloxy)methyl)-1-(3-(4-methoxyphenyl)propyl)piperidine hydrochloride

参考文献

1. Hanson DC, et al. Br J Pharmacol. 1999 Apr;126(8):1707-16.

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