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首页-小分子抑制剂&激动剂-Apoptosis-Ferroptosis-UAMC-3203
UAMC-3203

Chemical Structure : UAMC-3203

CAS No.: 2271358-65-5

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UAMC-3203 (UAMC3203)

货号: PC-35743Not For Human Use, Lab Use Only.

UAMC-3203 is a novel potent, drug-like ferroptosis inhibitor with IC50 of 12 nM, inhibit erastin-induced ferroptotic cell death more potently than Ferrostatin-1.

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10 mg ￥780 In stock
25 mg ￥1280 In stock
50 mg ￥1980 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

UAMC-3203 is a novel potent, drug-like ferroptosis inhibitor with IC50 of 12 nM, inhibit erastin-induced ferroptotic cell death more potently than Ferrostatin-1.
UAMC-3203 shows an improved protection compared to Fer-1 against multi-organ injury in mice.
UAMC-3203 epresents novel lead compounds with therapeutic potential in relevant ferroptosis-driven disease models.

物理化学性质&存储条件

分子量 508.122
分子式 C25H38ClN5O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-(benzylamino)-4-(cyclohexylamino)-N-(2-(piperazin-1-yl)ethyl)benzenesulfonamide hydrochloride

参考文献

1. Devisscher L, et al. J Med Chem. 2018 Oct 25. doi: 10.1021/acs.jmedchem.8b01299.

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