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Tubercidin

Chemical Structure : Tubercidin

CAS No.: 69-33-0

Tubercidin (Sparsomycin A, 7-Deazaadenosine, NSC 56408)

货号: PC-42061Not For Human Use, Lab Use Only.

Tubercidin (7-Deazaadenosine) is an antibiotic and adenosine analog isolated from the bacterium Streptomyces tubercidicus with potential antineoplastic activity.

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生物&药学活性

Tubercidin (7-Deazaadenosine) is an antibiotic and adenosine analog isolated from the bacterium Streptomyces tubercidicus with potential antineoplastic activity.
Tubercidin incorporates into DNA and inhibits polymerases, thereby inhibiting DNA replication and RNA and protein synthesis.
Tubercidin also exhibits antifungal and antiviral activities.

物理化学性质&存储条件

分子量 266.2533
分子式 C11H14N4O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 30 mg/mL

Chemical Name/SMILES

7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 7-β-D-ribofuranosyl-

参考文献

1. Mooberry SL, et al. Cancer Lett. 1995 Sep 25;96(2):261-6.

2. Olsen DB, et al. Antimicrob Agents Chemother. 2004 Oct;48(10):3944-53.

3. Drew ME, et al. J Biol Chem. 2003 Nov 21;278(47):46596-600.

4. Aoki JI, et al. Parasitol Res. 2009 Jan;104(2):223-8.

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