Topotecan hydrochloride

Chemical Structure : Topotecan hydrochloride

CAS No.: 119413-54-6

加入收藏

货号: PC-28737Not For Human Use, Lab Use Only.

Topotecan hydrochloride is (SKF104864A, NSC 609669) is an orally active topoisomerase I (TOP1) inhibitor, induces cell cycle arrest in G0/G1 and S phases and promotes apoptosis in mutiple cancer cells, also inhibits preribosomal subunit formation via binding to RPL15, activates STING-mediated antitumor immune responses.

规格	价格	库存
25 mg	￥580	In stock
50 mg	￥880	In stock
100 mg	￥1280	In stock
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

物理化学性质&存储条件

分子量	457.91
分子式	C23H24ClN3O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-10-((Dimethylamino)methyl)-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione hydrochloride

参考文献

1. Zhang FL, et al. PLoS One. 2013 Nov 26;8(11):e81815.

2. Yamada S, et al. J Immunol. 2022 Jul 1;209(1):171-179.

3. Kumar S, et al. Clin Cancer Res. 2011 Sep 1;17(17):5656-67.