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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Xanthine Oxidase (XAO)-Topiroxostat
Topiroxostat

Chemical Structure : Topiroxostat

CAS No.: 577778-58-6

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Topiroxostat (FYX-051, FYX051)

货号: PC-20358Not For Human Use, Lab Use Only.

Topiroxostat (FYX-051, FYX051) is potent xanthine oxidoreductase (XOR) inhibitor with IC50 of 5.3 nM.

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50 mg ￥980 In stock
100 mg ￥1480 In stock
250 mg ￥2580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Topiroxostat (FYX-051, FYX051) is potent xanthine oxidoreductase (XOR) inhibitor with IC50 of 5.3 nM.
Topiroxostat (FYX-051) exhibits extremely potent effect in lowering the serum uric acid (UA) levels in vivo and has good pharmacokinetic properties.

物理化学性质&存储条件

分子量 248.25
分子式 C13H8N6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-(2-cyano-4-pyridyl)-5-(4-pyridyl)-1,2,4-triazole

参考文献

1. Sato T, et al. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6225-9.

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