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首页-抗体和重组蛋白-Biosimilar Antibody-Tiragolumab
Tiragolumab

Chemical Structure : Tiragolumab

CAS No.: 1918185-84-8

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Tiragolumab (Anti-human TIGIT mAb, human IgG1-Kappa)

货号: PC-Ab1006Not For Human Use, Lab Use Only.

The first anti-TIGIT (T-cell immunoglobin and ITIM domain protein) mAb, prevent TIGIT from binding to its ligand, could restore the antitumor response and could complement the activity of anti–PD-L1/PD-1 antibodies. Anti-TIGIT mAb (tiragolumab) has demonstrated promising clinical efficacy in non-small cell lung cancer treatment when combined with an anti-PD-L1 drug (Tecentriq), exhibited remarkable efficacy in PD-L1-positive NSCLC patients in phase II clinical trials..

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1 mg ￥3580 In stock
5 mg ￥7580 In stock
10 mg ￥12800 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

The first anti-TIGIT (T-cell immunoglobin and ITIM domain protein) mAb, prevent TIGIT from binding to its ligand, could restore the antitumor response and could complement the activity of anti–PD-L1/PD-1 antibodies. Anti-TIGIT mAb (tiragolumab) has demonstrated promising clinical efficacy in non-small cell lung cancer treatment when combined with an anti-PD-L1 drug (Tecentriq), exhibited remarkable efficacy in PD-L1-positive NSCLC patients in phase II clinical trials.

物理化学性质&存储条件

分子量
分子式 Human IgG1-Kappa
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES

Tiragolumab; MTIG7192A; Anti-human TIGIT; VSTM3; T cell Ig and ITIM domain; T cell immunoreceptor with Ig and ITIM domains; V-set and transmembrane domain-containing protein 3; WUCAM

参考文献

1. 1, Yeo J, et al. Pharmaceuticals (Basel). 2021 Feb 28;14(3):200. 2, Houssaini MS, et al. Cancer Treat Res Commun. 2020;25:100239. 

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