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首页-抗体药物偶连体和PROTACs-E3 Ligase Ligand-Thalidomide-O-COOH
Thalidomide-O-COOH

Chemical Structure : Thalidomide-O-COOH

CAS No.: 1061605-21-7

Thalidomide-O-COOH (E3 Ligase Ligand 3, Cereblon ligand 3)

货号: PC-60108Not For Human Use, Lab Use Only.

Thalidomide-O-COOH (Cereblon ligand 3) is a Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein for PROTAC design.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Thalidomide-O-COOH (Cereblon ligand 3) is a Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein for PROTAC design.

物理化学性质&存储条件

分子量 332.268
分子式 C15H12N2O7
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetic acid

参考文献

1. Lohbeck J, et al. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5260-5262.

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