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首页-抗体药物偶连体和PROTACs-E3 Ligase Ligand-Thalidomide-4-OH
Thalidomide-4-OH

Chemical Structure : Thalidomide-4-OH

CAS No.: 5054-59-1

Thalidomide-4-OH (E3 Ligase Ligand 2, Cereblon ligand 2)

货号: PC-60101Not For Human Use, Lab Use Only.

Thalidomide-4-OH (Cereblon ligand 2) is a Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein for PROTAC design.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Thalidomide-4-OH (Cereblon ligand 2) is a Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein for PROTAC design.

物理化学性质&存储条件

分子量 274.232
分子式 C13H10N2O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(2,6-dioxopiperidin-3-yl)-4-hydroxyisoindoline-1,3-dione

参考文献

1. Robb CM, et al. Chem Commun (Camb). 2017 Jul 4;53(54):7577-7580.

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