Ternatin

Chemical Structure : Ternatin

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货号: PC-28176Not For Human Use, Lab Use Only.

Ternatin is a highly N-methylated cyclic heptapeptide and potent inhibitor of fat accumulation against 3T3-L1 murine adipocytes with EC50 of 0.14 ug/mL, shows antiperoxidative effect against lipid peroxidation, targets eukaryotic elongation factor-1A (eEF1A) and inhibits protein synthesis, shows cytotoxicity to cancer cells.

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生物&药学活性

Ternatin is a highly N-methylated cyclic heptapeptide and potent inhibitor of fat accumulation against 3T3-L1 murine adipocytes with EC50 of 0.14 ug/mL, shows antiperoxidative effect against lipid peroxidation, targets eukaryotic elongation factor-1A (eEF1A) and inhibits protein synthesis, shows cytotoxicity to cancer cells.

物理化学性质&存储条件

分子量	737.97
分子式	C37H67N7O8
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Cyclo[N-methyl-L-alanyl-N-methyl-D-alanyl-(3R)-3-hydroxy-D-leucyl-D-alloisoleucyl-N-methyl-L-alanyl-N-methyl-L-leucyl-L-leucyl]

参考文献

1. Shimokawa K, et al. Bioorg Med Chem Lett. 2007 Aug 15;17(16):4447-9.

2. Souza MF, et al. Phytomedicine. 1997 Mar;4(1):27-31.

3. Carelli JD, et al. Elife. 2015 Dec 10;4:e10222.

Ternatin

生物&药学活性

物理化学性质&存储条件

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Ternatin

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物理化学性质&存储条件

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