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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Factor Xa-Tedixaban
Tedixaban

Chemical Structure : Tedixaban

CAS No.: 1333126-80-9

Tedixaban (DD217, DD-217)

货号: PC-26359Not For Human Use, Lab Use Only.

Tedixaban (DD217) is a highly potent, selective Factor Xa (FXa) inhibitor with IC50 of 0.5 nM, doubled the prothrombin time (PTx2) value of 0.08 uM, a potent anticoagulant acting compound.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Tedixaban (DD217) is a highly potent, selective Factor Xa (FXa) inhibitor with IC50 of 0.5 nM, doubled the prothrombin time (PTx2) value of 0.08 uM, a potent anticoagulant acting compound.

物理化学性质&存储条件

分子量 435.91
分子式 C23H22ClN5O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzamide, N-(5-chloro-2-pyridinyl)-2-[[4-[(1-iminoethyl)methylamino]benzoyl]amino]-5-methyl-

参考文献

1. Patent WO2011108963 A1.

2. Tarasov DN, et al. Curr Drug Discov Technol. 2018;15(4):335-350.

3. Shulga DA, et al. J Biomol Struct Dyn. 2023 Jul;41(10):4723-4734.

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