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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Fungal-Tavaborole
Tavaborole

Chemical Structure : Tavaborole

CAS No.: 174671-46-6

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Tavaborole (AN-2690, AN 2690)

货号: PC-42761Not For Human Use, Lab Use Only.

AN-2690 (Tavaborole) is an antifungal compound that inhibits cytoplasmic leucyl-tRNA synthetase (LeuRS) for the potential treatment of nnychomycosis.

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50 mg ￥480 In stock
100 mg ￥780 In stock
250 mg ￥1180 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

AN-2690 (Tavaborole) is an antifungal compound that inhibits cytoplasmic leucyl-tRNA synthetase (LeuRS) for the potential treatment of nnychomycosis.
AN-2690 inhibits T. rubrum, T. mentagrophytes, C. albicans, C. neoformans with MIC50s of 0.25-1ug/mL.

物理化学性质&存储条件

分子量 151.9307
分子式 C7H6BFO2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2,1-Benzoxaborole, 5-fluoro-1,3-dihydro-1-hydroxy-

参考文献

1. Baker SJ, et al. J Med Chem. 2006 Jul 27;49(15):4447-50.

2. Rock FL, et al. Science. 2007 Jun 22;316(5832):1759-61.

3. Sarkar J, et al. FEBS Lett. 2011 Oct 3;585(19):2986-91.

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