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首页-小分子抑制剂&激动剂-GPCR-Lysophospholipid Receptor-Tamuzimod
Tamuzimod

Chemical Structure : Tamuzimod

CAS No.: 2097854-81-2

Tamuzimod (VTX002, VTX-002)

货号: PC-24944Not For Human Use, Lab Use Only.

Tamuzimod (VTX002) is a peripherally-restricted, potent and selective, orally bioavailable small molecule modulator of sphingosine-1-phosphate-1 receptor (S1PR1, S1P1 receptor) in development for the treatment of ulcerative colitis (UC).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Tamuzimod (VTX002) is a peripherally-restricted, potent and selective, orally bioavailable small molecule modulator of sphingosine-1-phosphate-1 receptor (S1PR1, S1P1 receptor) in development for the treatment of ulcerative colitis (UC).

物理化学性质&存储条件

分子量 546.71
分子式 C21H13Cl3F3N5O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-Piperidinone, 5-[2,5-dichloro-4-[5-[8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-1,2,4-oxadiazol-3-yl]phenoxy]-, (5R)-

参考文献

1. Patent WO2018211324 A1.

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