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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-TXA09155
TXA09155

Chemical Structure : TXA09155

CAS No.: 2243960-05-4

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TXA09155 (TXA-09155)

货号: PC-26645Not For Human Use, Lab Use Only.

TXA09155 is a small molecule efflux pump inhibitor, shows synergistic effect with levofloxacin against multidrug resistant P. aeruginosa clinical isolates, shows ≥8-fold potentiation of levofloxacin, moxifloxacin, doxycycline, minocycline, cefpirome, chloramphenicol, and cotrimoxazole at 6.25 ug/mL.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

TXA09155 is a small molecule efflux pump inhibitor, shows synergistic effect with levofloxacin against multidrug resistant P. aeruginosa clinical isolates, shows ≥8-fold potentiation of levofloxacin, moxifloxacin, doxycycline, minocycline, cefpirome, chloramphenicol, and cotrimoxazole at 6.25 ug/mL.

物理化学性质&存储条件

分子量 366.44
分子式 C21H23FN4O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(((2S,4R)-4-(aminomethyl)pyrrolidin-2-yl)methyl)-6-(4-fluorophenyl)-1H-indole-2-carboxamide

参考文献

1. Zhang Y, et al. Antibiotics (Basel). 2022 May 26;11(6):716.

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